Potassium Binders Facilitate Continued RAASi Therapy: Helpful Tips for Clinicians

Potassium Binders Facilitate Continued RAASi Therapy: Helpful Tips for Clinicians    

Potassium Binders Facilitate Continued RAASi Therapy: Helpful Tips for Clinicians

Discover the importance of optimizing RAASi therapy in patients with heart failure and how using potassium binders can help achieve better outcomes.

Available credits: 0.25

Time to complete: 15 minutes


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  • Overview

    There is clinical trial-supported evidence for the use of renin-angiotensin-aldosterone system inhibitors (RAASi) in patients with heart failure and reduced ejection fraction. RAASi therapy improves both morbidity and mortality outcomes, and its use is now recommended in published guidelines. However, the achievement of target dosing is often limited or interrupted due to the development of hyperkalemia. 

    In this case-based activity, Drs. Javed Butler and Ileana Piña discuss the importance of optimizing RAASi therapy in patients with heart failure and how the use of potassium binders can help accomplish this goal. They will also review the risks and benefits of potassium binders, in addition to both short- and long-term use of these agents in the treatment of patients with heart failure.

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Commercial Support, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. GLC resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Ileana L. Piña, MD, MPH, FAHA, FACC
    Clinical Professor of Medicine
    College of Medicine
    Central Michigan University
    Mount Pleasant, MI

    Consulting Fees: Novartis, Relypsa

    Javed Butler, MD, MBA, MPH
    Professor & Chair, Department of Medicine
    University of Mississippi Medical Center
    Jackson, MS

    Consulting Fees: Abbott, Adrenomed, Amgen, Array, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol Myers Squibb, CVRx, G3 Pharmaceuticals, Impulse Dynamics, Innolife, Janssen, LivaNova, Luitpold, Medtronic, Merck, Novartis, Novo Nordisk, Relypsa, Roche, V-Wave Ltd., Vifor Pharma

    Reviewers/Content Planners/Authors:

    • Nancy Ashley, MSN, APRN, ANP-BC, CCRN, CEN, has nothing to disclose.
    • Sean T. Barrett has nothing to disclose.
    • Megan Clem has nothing to disclose.
    • Amanda Hilferty has nothing to disclose.
    • William A. Mencia, MD, FACEHP, CHCP, has nothing to disclose.
    • Ileana L. Piña, MD, MPH, FAHA, FACC receives consulting fees from Novartis and Relypsa.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Discuss the importance of maximizing RAASi therapy to improve outcomes in patients with heart failure
    • Differentiate the risks and benefits of currently available potassium binders
    • Develop strategies for using potassium binders to manage heart failure short or long term to improve patient outcomes
  • Target Audience

    This activity is designed to meet the educational needs of cardiologists, nephrologists, primary care physicians, and all allied healthcare professionals involved in the diagnosis and treatment of HF and CKD.

  • Accreditation and Credit Designation Statements

    Global Learning Collaborative is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    Global Learning Collaborative designates this enduring material for a maximum of .25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    ReachMD Healthcare Image

    Dedicated to the creation and execution of the highest quality, evidence-based continuing medical education (CME) initiatives, we utilize multiple learning opportunities for the primary goal of improving healthcare delivered to patients through sharing of research, knowledge, and clinical practice skills.

  • Commercial Support

    This activity is supported by an independent educational grant from Vifor Pharma.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Medtelligence. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Medtelligence you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.
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