Don’t Let Hyperkalemia Get You Down When Potassium Goes Up in Your Patients with Heart Failure

Don’t Let Hyperkalemia Get You Down When Potassium Goes Up in Your Patients with Heart Failure

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How do you approach hyperkalemia in your patients with heart failure? Our experts offer strategies to for maintaining GDMT while lowering potassium. 

Available credits: 0.25

Time to complete: 15 minutes


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  • Overview

    In heart failure, there is a propensity to down-titrate or discontinue guideline-directed medical therapy in the presence of hyperkalemia, even though it is well known that suboptimal use of these therapies leads to poorer outcomes for our patients with heart failure and chronic kidney disease. Join Drs. Javed Butler, Ileana Piña, and Patrick Rossignol as they take a multidisciplinary approach to a patient case and discuss dosing and other treatment decisions.

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Javed Butler, MD, MBA, MPH

    President, Baylor Scott and White Research Institute
    Dallas, TX
    Distinguished Professor of Medicine, University of Mississippi Medical Center
    Jackson, MS, USA

    Consulting Fees: Abbott, Adrenomed, Amgen, Array, AstraZeneca, Bayer, Boehringer-Ingelheim, Bristol Myers Squibb, CVRx, G3 Pharmaceuticals, Impulse Dynamics, Innolife, Janssen, LivaNova, Luitpold, Medtronic, Merck, Novartis, Novo Nordisk, Relypsa, Roche, V-Wave Ltd., Vifor Pharma

    Ileana L. Piña, MD, MPH, FAHA, FACC
    Professor and Quality Officer, Heart & Vascular Service Line
    Sidney Kimmel Medical College
    Thomas Jefferson University
    Philadelphia, PA

    Consulting Fees: Novartis, Relypsa

    Patrick Rossignol, MD, PhD
    Head of Medical Specialties Service (Nephrology–Haemodialysis)
    Princess Grace Hospital
    Medical Director, Monaco Private Haemodialysis Centre
    Monaco, France

    Consulting Fees: Ablative Solutions, AstraZeneca, Bayer, Boehringer-Ingelheim, CinCor, Corvidia, CVRx, Fresenius, G3P, Grunenthal, Idorsia, KBP, Novartis, Novo Nordisk, Relypsa, Sanofi, Sequana Medical, Servier, Stealth Peptides, Vifor Fresenius Medical Care Renal Pharma
    Contracted Research: Vifor Pharma
    Ownership Interest: CardioRenal, G3P

    Reviewers/Content Planners/Authors:

    • Megan Clem has nothing to disclose.
    • Cindy Davidson has nothing to disclose.
    • Ann Early has nothing to disclose.
    • Amanda Hilferty has nothing to disclose.
    • Mario P. Trucillo, PhD, MS, has nothing to disclose. 
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Discuss the clinical impact of hyperkalemia on optimized guideline-directed medical therapy in patients with heart failure with reduced ejection fraction (HFrEF) and chronic kidney disease (CKD)
    • Apply guideline-directed recommendations for addressing hyperkalemia in patients with HFrEF and CKD
    • Identify key clinical considerations for patients with HFrEF and CKD when using a potassium binder
  • Target Audience

    This activity is designed to meet the educational needs of cardiologists, nephrologists, primary care physicians, and all other professionals involved in the identification and treatment of heart failure.

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

    Global Learning Collaborative (GLC) designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for 0.25 nursing contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.


  • Provider(s)/Educational Partner(s)

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    Our ultimate goal is to improve the care being delivered to patients, and our high-quality, evidence-based CME initiatives reflect our dedication to the creation and execution of excellence and are the product of shared research, knowledge, and clinical practice skills across the healthcare continuum.

  • Commercial Support

    This activity is supported by an independent educational grant from CSL Vifor.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Medtelligence. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Medtelligence you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Reproduction Prohibited
    Reproduction of this material is not permitted without written permission from the copyright owner.

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